The preparation of 2'-deoxy-2'-fluoro-1',2'-seconucleosides as potential antiviral agents

DOI: 10.1021/jm00164a035

Source and publish data:

Journal of Medicinal Chemistry p. 681 - 686 (1990)

Update date:2022-08-03

Topics:

Authors:

Vemishetti

Saibaba Saibaba

Panzica Panzica

Abushanab

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00164a035

The preparation of (R,R)-1,3-dibenzyl-4-fluorobutane-1,2,3-triol (6) from D-isoascorbic acid and subsequent chloromethylation of this chiron made possible the synthesis of a series of 2'-deoxy-2'-fluoro-1,2'-seconucleosides. Among them were the uridine (1

Full text of DOI:10.1021/jm00164a035

Products guided by the article

Product name:(R,R)-3-O-benzyl-4-fluoro-1,2,3-butanetriol

Cas No:123903-54-8

R&D Labs maybe for 123903-54-8

QINGDAO TAOSIGN INTERNATIONAL TRADE CO.,LIMITED

Contact:+86-0532-82683616

Address:RM1402, Doublestar Seacoase 7#, No. 5 Guizhou Road, Qingdao, Shandong, China
Feis International Trade Co,. Ltd

Contact:13961823444-18235944442

Address:Wuxi jiangsu
Chongqing Werlchem Fine Chemical Co. Ltd

Contact:+86-23-67521957

Address:NO.15,Fortune Road,Yubei District,401121,Chongqing,China
Anhui Hope-Chem Co., Ltd.

Contact:86-551-63540590

Address:No 1388 Furong Rd., Hefei, Anhui, China
Jinan Great Chemical Co.,Ltd.

Contact:+86-531-58668191 58668193 58668196 58661173

Address:No 55,Beixiaoxinzhuang West Street,Jinan City, Shandong Province

Relevant to this article

Synthesis and in vitro/in vivo pharmacological evaluation of [ ¹¹C]-ThioABP, a novel radiotracer for imaging mGluR5 with PET

Doi:10.1039/c2md20332d
(2013)
Domino [3+3] annulation/ring-cleavage reactions of 1,3- bis(trimethylsilyloxy)-1,3-butadienes with 5-aryl- and 5-vinyl-3-acyl-4,5- dihydrofurans: Efficient synthesis of 5-(4-chlorobut-2-en-1-yl)- and 5-(2-aryl-2-chloroethyl)salicylates

Doi:10.1002/ejoc.201000158
(2010)
Synthesis, molecular modeling, and biological evaluation of cinnamic acid metronidazole ester derivatives as novel anticancer agents

Doi:10.1016/j.bmc.2010.06.003
(2010)
Synthesis and pharmacological evaluation of pyrazine N-acylhydrazone derivatives designed as novel analgesic and anti-inflammatory drug candidates

Doi:10.1016/j.bmc.2010.06.002
(2010)
Homolytic reactions of N-bromohexamethyldisilazane with trialkyl(phenylalkoxy) derivatives of silicon and tin

Doi:10.1134/S1070363210050117
(2010)
Synthesis of Enantiomeric Aminoalkylcarbamoylphosphonates and Their Evaluation as Dual-Action Anticancer MMP and Carbonic Anhydrase Inhibitors

Doi:10.1002/hc.21256
(2015)

Article Doi