The preparation of 2'-deoxy-2'-fluoro-1',2'-seconucleosides as potential antiviral agents

DOI: 10.1021/jm00164a035

Source and publish data:

Journal of Medicinal Chemistry p. 681 - 686 (1990)

Update date:2022-08-03

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Authors:

Vemishetti

Saibaba Saibaba

Panzica Panzica

Abushanab

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Article abstract of DOI:10.1021/jm00164a035

The preparation of (R,R)-1,3-dibenzyl-4-fluorobutane-1,2,3-triol (6) from D-isoascorbic acid and subsequent chloromethylation of this chiron made possible the synthesis of a series of 2'-deoxy-2'-fluoro-1,2'-seconucleosides. Among them were the uridine (1

Full text of DOI:10.1021/jm00164a035

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