5-Endo-Trig Cyclisation and 1,3-Anionic Cycloaddition in Arylimine Derivatives of α-Amino Acid Esters

DOI: 10.1039/c39800000648

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 648 - 650 (1980)

Update date:2022-08-03

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Authors:

Grigg, Ronald

Kemp, James

Malone, John

Tangthongkum, Anant

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Article abstract of DOI:10.1039/c39800000648

Michael adducts of imines of α-amino acid esters are converted into a mixture of two stereoisomeric pyrrolidines by benzyltrimethylammonium methoxide (BTAM) apparently by a 5-endo-trig cyclisation.

Full text of DOI:10.1039/c39800000648

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