
Synlett p. 1631 - 1634 (2010)
Update date:2022-08-06
Topics:
Ranaivondrambola, Tsiresy
Hatton, Wilfried
Felpin, Franois-Xavier
Evain, Michel
Mathe-Allainmat, Monique
Lebreton, Jacques
The first synthesis of a racemic nicotine-lobeline hybrid is described based on a diastereoselective allylation and an RCM reaction as key steps. This synthetic route paves the way to the preparation of original potential ligands of nAChRs. Georg Thieme Verlag Stuttgart New York.
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