New quinolone antibacterial agents. Synthesis and biological activity of 7-(3,3- or 3,4-disubstituted-1-pyrrolidinyl)quinoline-3-carboxylic acids

DOI: 10.1021/jm00164a060

Source and publish data:

Journal of Medicinal Chemistry p. 849 - 854 (1990)

Update date:2022-09-26

Topics:

Authors:

Hagen Hagen

Domagala

Heifetz Heifetz

Sanchez Sanchez

Solomon Solomon

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00164a060

A series of 7-(3-amino- or 3-aminomethyl-1-pyrrolidinyl)-1-cyclopropyl-6,8-difluoro-1,4-dihydro- 4-oxo-3-quinolinecarboxylic acids was synthesized and tested for antibacterial activity. Unique to these quinolones was the presence of a methyl or phenyl gro

Full text of DOI:10.1021/jm00164a060

Products guided by the article

Product name:4-phenyl-1-(phenylmethyl)-3-pyrrolidinemethanamine

Cas No:124563-10-6

R&D Labs maybe for 124563-10-6

Jiangsu Zhenfang Chemical CO.,LTD.(Suzhou Zhenfang Chemical Factory)

Contact:+86-512-69598882

Address:Room1201, Jiayuan Road No.1018, Xiangcheng District, Suzhou, China
Changsha Nutritopper Bio Technology Co.,Ltd.

Contact:+86-731-87803543

Address:East 1st Street, Baima Road, Ningxiang County
Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

website:http://www.jlpharms.com

Contact:86-571-86982636

Address:Rm A606, Fuyi Center, jianqiao street
Shandong Wanda Organosilicon New Material Co., Ltd

Contact:+86-21-54177116;54302881

Address:R1318 Greenland No. 3 Lane 58 Xinjian East Rd., Minhang
Shanghai Forever Biotech Co., Ltd.

Contact:+86-21-69734790

Address:Room 5017/5019、5022、5024 of Technology Innovation Centre, No.1155, Gongyuan East Rd, QingPu District, Shanghai China.

Relevant to this article

Doi:10.1021/jm50017a014
(1961)
Application of an enyne metathesis/diels-alder cycloaddition sequence: A new versatile approach to the syntheses of C-Aryl glycosides and spiro- C-Aryl glycosides

Doi:10.1002/chem.201000482
(2010)
A facile synthesis of 2,3-azaisoindoline

Doi:10.1016/j.tetlet.2010.08.091
(2010)
Complexation of alkali metal cations by conformationally rigid, stereoisomeric calix[4]arene crown ethers: A quantitative evaluation of preorganization

Doi:10.1021/ja00175a035
(1990)
Selective enrichment and identification of azide-tagged cross-linked peptides using chemical ligation and mass spectrometry

Doi:10.1016/j.jasms.2010.04.004
(2010)
Synthesis of N ²-Alkyl-8-oxo-7,8-dihydro-2′-deoxyguanosine derivatives and effects of these modifications on RNA duplex stability

Doi:10.1021/jo102187y
(2011)

Article Doi