Structural requirements for agonist actions at the benzodiazepine receptor: Studies with analogues of 6-(benzyloxy)-4-(methoxymethyl)-β-carboline-3-carboxylic acid ethyl ester

DOI: 10.1021/jm00165a028

Source and publish data:

Journal of Medicinal Chemistry p. 1062 - 1069 (1990)

Update date:2022-07-29

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Authors:

Hollinshead

Trudell Trudell

Skolnick

Cook Cook

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Article abstract of DOI:10.1021/jm00165a028

The analogues 2, 3, 8a-c, 9, 13, and 14 of the β-carboline 6-(benzyloxy)-4-(methoxymethyl)-β-carboline-3-carboxylic acid ethyl ester (ZK-93423, 1) were synthesized in order to determine which functional groups are required for agonist activity exhibited b

Full text of DOI:10.1021/jm00165a028

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