SOLID-STATE NUCLEOPHILIC AROMATIC SUBSTITUTION REACTION OF A CARBOXYLIC ACID COCRYSTAL

DOI: 10.1016/S0040-4039(01)80463-9

Source and publish data:

Tetrahedron Letters p. 3617 - 3620 (1989)

Update date:2022-09-26

Topics:

Authors:

Etter, M.C.

Frankenbach, G.M.

Bernstein, J.

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Article abstract of DOI:10.1016/S0040-4039(01)80463-9

A facile thermally activated aromatic nucleophilic substitution reaction is shown to take place in the solid state in cocrystals of 4-chloro-3,5-dinitrobenzoic acid and 4-aminobenzoic acid.The cocrystals are also made in the solid state by grinding the two acids together at room temperature.

Full text of DOI:10.1016/S0040-4039(01)80463-9

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