Synthesis, in-vitro cytotoxicity, and a preliminary structure-activity relationship investigation of pyrimido[4,5-c]quinolin-1(2H)-ones

DOI: 10.1002/ardp.200900281

Source and publish data:

Archiv der Pharmazie p. 465 - 472 (2010)

Update date:2022-08-04

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Authors:

Metwally, Kamel

Khalil, Ashraf

Pratsinis, Harris

Kletsas, Dimitris

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Article abstract of DOI:10.1002/ardp.200900281

As part of our ongoing research effort to develop new antimitotic agents based on the recently reported pyrimido[4,5-c]quinoline-1(2H)-one ring skeleton, we were interested in identifying structural elements that contribute to the cytotoxicity of this cla

Full text of DOI:10.1002/ardp.200900281

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