Synthesis and evaluation of novel analogues of vitamin B6 as reactivators of tabun and paraoxon inhibited acetylcholinesterase

DOI: 10.1016/j.cbi.2010.02.004

Source and publish data:

Chemico-Biological Interactions p. 234 - 237 (2010)

Update date:2022-08-03

Topics: Characterization Structure-Activity Relationship (SAR) Studies In Vivo Studies Regulatory Approval Design and Synthesis Biochemical Assays Pharmacokinetics and Pharmacodynamics Scale-up and Production Toxicology Studies Formulation and Drug Development

Authors:

Ga?o-Soka?, Dajana

Katalini?, Maja

Kovarik, Zrinka

Bu?i?, Valentina

Kova?, Spomenka

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Article abstract of DOI:10.1016/j.cbi.2010.02.004

A series of novel pyridinium oximes was prepared by reactions of quaternization of pyridoxal oxime with substituted phenacyl bromides in acetone at room temperature. The structures of compounds were determined according to the data obtained by IR spectros

Full text of DOI:10.1016/j.cbi.2010.02.004

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