A TOTAL SYNTHESIS OF MAGALLANESINE: DMF ACETAL MEDIATED CYCLODEHYDRATION OF A METHYL KETONE THIOIMIDE

DOI: 10.1016/S0040-4039(00)99114-7

Source and publish data:

Tetrahedron Letters p. 2743 - 2746 (1989)

Update date:2022-09-26

Topics:

Authors:

Fang, Francis G.

Feigelson, Gregg B.

Danishefsky, Samuel J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)99114-7

An amide acetal-mediated intramolecular condensation of a methylketone with a regioselectively activated unsymmetrical phthalimide resulted in the total synthesis of the isoindolobenzazocine alkaloid magallanesine (1).

Full text of DOI:10.1016/S0040-4039(00)99114-7

Products guided by the article

Product name:2,3-Dimethoxy-6-(5-methylene-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinoline-6-carbonyl)-benzoic acid ethyl ester

Cas No:125730-83-8

R&D Labs maybe for 125730-83-8

Suzhou CarbonWell Pharma-Tech Co., Ltd

Contact:Tel: + 86 (0)512-8898-1216; + 86-18606258602

Address:2358 Changan Road, Wujiang Scientific Innovation Park, Wujiang, Jiangsu Province, P. R. China 215200
Beijing Zhongshuo Pharmaceutical T & D Co.,Ltd

Contact:0086-10-64430626

Address:ea No 16, HEPINGLI,DONGCHENG DISTRICT,BEIJING,P.R.CHINA.
Taizhou KEDE Chemical.Co.,Ltd.

Contact:86-576-84613060

Address:Jiangkou Chemical Zoon
ZiBO KuoDing Trade company Ltd

website:http://www.sdzbkd.com

Contact:86-13361591822

Address:GongQingTuan road
Xinjiang Fufeng Biotechnologies Co., Ltd.

Contact:+86-539-7287111

Address:GANQUANPU INDUSTRIAL PARK, ECONOMIC AND TECHNOLOGICAL DEVELOPMENT AREA (TOUTUNHE DISTRICT) OF URUMQI

Relevant to this article

A gallium-catalyzed cycloisomerization/Friedel-Crafts tandem

Doi:10.1021/jo101709n
(2010)
Asymmetric cyclopropanation of alkenes with dimethyl diazomalonate catalyzed by chiral diene-rhodium complexes

Doi:10.1002/anie.201003775
(2010)
Ethacrynic acid analogues lacking the α,β-unsaturated carbonyl unit-Potential anti-metastatic drugs

Doi:10.1016/j.bmcl.2010.01.144
(2010)
Synthesis of spirocyclic carbazole- and acridine-lactams

Doi:10.1039/b922827f
(2010)
Substituted fused bicyclic pyrrolizinones as potent, orally bioavailable hNK₁ antagonists

Doi:10.1016/j.bmcl.2010.01.065
(2010)
Sequential synthesis of (E)-α,β-unsaturated primary amides with complete stereoselectivity

Doi:10.1021/jo100320j
(2010)

Article Doi