Journal of Heterocyclic Chemistry p. 1039 - 1043 (1989)
Update date:2022-08-05
Topics:
Yoshino
Hori
Hori
Morita
Tsukamoto
The regio specific synthesis of 5-fluorobenzothiazoles 14 has been accomplished by using difluorothiobenzanilides 13 as a key intermediate. Through this method, 5-fluorosubstituted fostedil 3 and its derivatives were synthesized and evaluated coronary vas
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