Organic phosphorus compounds. Part 3. Synthesis of 5-fluorosubstituted benzothiazolylbenzylphosphonates

DOI: 10.1002/jhet.5570260425

Source and publish data:

Journal of Heterocyclic Chemistry p. 1039 - 1043 (1989)

Update date:2022-08-05

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Authors:

Yoshino Yoshino

Hori Hori

Morita Morita

Tsukamoto

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Article abstract of DOI:10.1002/jhet.5570260425

The regio specific synthesis of 5-fluorobenzothiazoles 14 has been accomplished by using difluorothiobenzanilides 13 as a key intermediate. Through this method, 5-fluorosubstituted fostedil 3 and its derivatives were synthesized and evaluated coronary vas

Full text of DOI:10.1002/jhet.5570260425

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