Synthesis p. 709 - 710 (1989)
Update date:2022-09-26
Topics:
Cox, Brian
Waigh, Roger D.
Problems in the synthesis of 4-chromanones by condensation of 2-hydroxyacetophenones with formaldehyde can be avoided by the isolation of the Mannich base hydrochlorides and cyclization by titration with potassium hydroxide.
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