A Modified Synthesis of 4-Chromanones

DOI: 10.1055/s-1989-27369

Source and publish data:

Synthesis p. 709 - 710 (1989)

Update date:2022-09-26

Topics:

Authors:

Cox, Brian

Waigh, Roger D.

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Article abstract of DOI:10.1055/s-1989-27369

Problems in the synthesis of 4-chromanones by condensation of 2-hydroxyacetophenones with formaldehyde can be avoided by the isolation of the Mannich base hydrochlorides and cyclization by titration with potassium hydroxide.

Full text of DOI:10.1055/s-1989-27369

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