Bioorganic and Medicinal Chemistry Letters p. 16 - 20 (2017)
Update date:2022-09-26
Topics:
Zhang, Wenming
Holyoke, Caleb W.
Pahutski, Thomas F.
Lahm, George P.
Barry, James D.
Cordova, Daniel
Leighty, Robert M.
Singh, Vineet
Vicent, Daniel R.
Tong, My-Hanh T.
Hughes, Kenneth A.
McCann, Stephen F.
Henry, Yewande T.
Xu, Ming
Briddell, Twyla A.
A novel class of mesoionic pyrido[1,2-a]pyrimidinones has been discovered with exceptional insecticidal activity controlling a number of insect species. In this communication, we report the part of the optimization program which led to the discovery of triflumezopyrim as a highly potent insecticide controlling various hopper species. Our efforts in discovery, synthesis, structure-activity relationship elucidation, and biological activity evaluation are also presented.
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Doi:10.1021/ol102912g
(2011)Doi:10.1002/chem.201001457
(2010)Doi:10.1002/adsc.201000571
(2010)Doi:10.1021/ja00278a060
(1986)Doi:10.1021/ic101945d
(2011)Doi:10.1080/17415993.2012.684204
(2012)