Journal of Organic Chemistry p. 3622 - 3627 (1990)
Update date:2022-09-26
Topics:
Iwao, Masatomo
Chlorobenzene and its OMe, OSiMe2-t-Bu, and Cl derivatives 1 were lithiated with high regioselectivity ortho to chlorine by treatment with sec-BuLi in THF at -105 deg C without complications due to benzyne formation.The lithio species thus generated under
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