Tetrahedron Letters p. 6599 - 6602 (1989)
Update date:2022-08-05
Topics:
Gallagher, Timothy F.
Adams, Jerry L.
Several 6,7-dihydro<5H>pyrrolo<1,2-a>imidazoles were activated toward functionalization at C-7 by conversion to quaternary imidazolium salts.The MEMCl derived quaternary salts upon treatment with base reacted with both aldehydes and alkyl halides.The MEM group was removed under mild conditions by heating the functionalized adducts in a variety of solvents.
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