Journal of Medicinal Chemistry p. 10126 - 10140 (2018)
Update date:2022-08-15
Topics:
Devisscher, Lars
Van Coillie, Samya
Hofmans, Sam
Van Rompaey, Dries
Goossens, Kenneth
Meul, Eline
Maes, Louis
De Winter, Hans
Van Der Veken, Pieter
Vandenabeele, Peter
Berghe, Tom Vanden
Augustyns, Koen
Ferroptosis is an iron-catalyzed, nonapoptotic form of regulated necrosis that results in oxidative lipid damage in cell membranes that can be inhibited by the radical-trapping antioxidant Ferrostatin-1 (Fer-1). Novel inhibitors derived from the Fer-1 sca
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