Dynamic Aspects in Host-Guest Interactions. 3. Kinetics and Mechanism for Molecular Recognition by Hexakis(2,6-di-O-methyl)-α-cyclodextrin of Some Azo Guest Molecules

Article abstract of DOI:10.1021/j100011a039

The inclusion reactions of some azo guest molecules, 3'-Pr-4'-(OH)Ph-N=N-PhSO3^-Na⁺ (1), 3'-iPr-4'-(OH)Ph-N=N-PhSO3^-Na⁺ (2), and 3'-tBu-4'-(OH)Ph-N=N-PhSO3^-Na⁺ (3), with hexakis(2,6-di-O-methyl)-α-cyclodextrin (DM-αCDx) were investigated.The rates and mechanism for the inclusion reactions of 1, 2, and 3 with DM-αCDx have been determined.Enhanced binding ability with the guest and a threestep inclusion mechanism by DM-αCDx were found.