ASYMMETRIC SYNTHESIS OF TRANS-(2R,5R)-BIS(BENZYLOXYMETHYL)PYRROLIDINE

DOI: 10.1016/S0040-4039(01)93858-4

Source and publish data:

Tetrahedron Letters p. 6075 - 6076 (1989)

Update date:2022-07-31

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Authors:

Marzi, M.

Misiti, D.

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Article abstract of DOI:10.1016/S0040-4039(01)93858-4

Trans-(2R,5R)-bis(benzyloxymethyl)-pyrrolidine (1) was prepared from 1,2:5,6-diisopropylidene mannitol.Key transformations included the selective protection of primary hydroxy groups and stereocontrolled cyclization.

Full text of DOI:10.1016/S0040-4039(01)93858-4

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Product name:1,6-di-O-benzyl-2,5-di-O-tosyl-3,4-dideoxy-D-threo-hexitol

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