Synthesis and blood glucose lowering activity of some novel benzenesulfonylthiourea derivatives substituted with 6-aryl-4,5-dihyropyridazin- 3(2H)-ones

Article abstract of DOI:10.1007/s00044-010-9539-3

Some new benzenesulfonylthiourea derivatives substituted with pyridazinone (2a-o) were synthesized by refluxing the appropriate 6-aryl-2-(p-sulfamylphenyl) -4,5-dihydropyridazine-3(2H)-ones with isothiocyanate in dry acetone over anhydrous K₂CO