The preparation and photochemistry of 6-azido-4,5,6,7-trifluoroindole in toluene. Evaluation of a new reagent for photoaffinity labelling

Article abstract of DOI:10.1016/S0040-4039(01)88995-4

6-Azido-4,5,6,7-trifluoroindole 1 was synthesized and its photochemistry examined. Although photolysis of 1 at 25° invariably leads to tars, photolysis at -196° in frozen toluene produced a benzylic CH insertion adduct in 70-80% isolated yield. The data s