Regio- and stereospecific synthesis of substituted cyclohexenediols from 7-oxabicyclo[2.2.1]hept-5-en-2-ols and organolithium reagents

Article abstract of DOI:10.1016/S0040-4039(01)93916-4

The bridge opening reactions of 7-oxabicyclo[2.2.1]hept-5-en-2-ols, 4 and 6 with organolithium reagents proceed with complete regio- and stereoselectivity to produce highly functionalized cyclohexene derivatives 5 and 7, respectively.