A New Synthesis of Methyl α-Acetolactate based on Thiazolium Chemistry and modelled on the Enzymatic Synthesis of α-Acetolactate catalysed by Acetolactate Synthase

DOI: 10.1039/c39900000331

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 331 - 333 (1990)

Update date:2022-07-30

Topics:

Authors:

Crout, David H. G.

Lee, Edward R.

Pearson, David P.J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/c39900000331

Methyl α-acetolactate has been synthesised via a series of adducts with benzothiazole in a manner analogous to the enzymatic reaction catalysed by acetolactate synthase.

Full text of DOI:10.1039/c39900000331

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:1-(3-Methyl-2,3-dihydro-benzothiazol-2-yl)-ethanone

Cas No:127863-08-5

R&D Labs maybe for 127863-08-5

Tianjin Pharmacn Medical Technology Co.,Ltd.

Contact:86-22-60122566ext.866(English),23359620

Address:Green Industrial Base, 6 Haitaifazhan Sixth Rd., Huayuan Industrial Area, Tianjin, 300384, China
Taimai Sanluck Pharmaceutical Co.,Ltd

Contact:86-592-7662921

Address:8D,No.186,Huarong Road,Huli,Xiamen,China
Shanghai Sinofluoro Scientific Co., Ltd

Contact:+86-21-64279360

Address:Room 1006,Building 3,#58 East Xinjian Road, Shanghai ,201100,China,
Allicon Pharmaceuticals,Inc.

Contact:+86-519-86339586，13584329896

Address:Changzhou Scientific and Education Park
Suzhou Wedo Chemicals Co., Ltd.

Contact:86 512 58100425

Address:Zonger Road, DongSha Industry Park , Zhangjiagang, Jiangsu, China

Relevant to this article

Substituted quinolinones, part 14: Synthesis of novel dispiro(heterocycle- N,2′-[1,3]dithietane-4′,3″-quinolinedione) derivatives under PTC conditions

Doi:10.1080/10426507.2010.496746
(2011)
Pentafluorophenyl Substitution of Natural Di(indol-3-yl)methane Strongly Enhances Growth Inhibition and Apoptosis Induction in Various Cancer Cell Lines

Doi:10.1002/cbdv.201900028
(2019)
Doi:10.1039/jr9490001163
(1949)
A Convenient Synthesis of Primary Amines Using Sodium Diformylamide as A Modified Gabriel Reagent

Doi:10.1055/s-1990-26805
(1990)
Identification and Profiling of Hydantoins - A Novel Class of Potent Antimycobacterial DprE1 Inhibitors

Doi:10.1021/acs.jmedchem.8b01356
(2018)
Beyond the Corey–Chaykovsky Reaction: Synthesis of Unusual Cyclopropanoids via Desymmetrization and Thereof

Doi:10.1002/asia.201901108
(2019)

Article Doi