Tetrahedron p. 6771 - 6790 (1989)
Update date:2022-08-04
Topics:
Barnish, Ian T.
Fishwick, Colin W. G.
Hill, David R.
Szantay, Csaba
A method has been developed for the efficient generation of 2-(N-acylamino)-1-thia-1,3-dienes.These novel hetero-dienes, which are generated via acylation of the corresponding thioamides, undergo irreversible regio- and stereospecific Diels-Alder addition to the starting thioamides to yield 6-(N-acylamino)-3,4-dihydro-2H-thiopyrans.The regiochemistry, relative configurations and the major solution conformations of the thiopyrans 4a-c and 10 have been determined using NMR techniques.In addition, it has been found that these systems exhibit a number of unique physical and chemical properties.
View MoreContact:86+21-56421993
Address:3F,BUILDING 10,NO.2889 JINKE ROAD, SHANGHAI.
Luojiang Chenming Biological Products Co
Contact:+86 15000297032
Address:GROUP NO.4, HE SHENG VILLAGE, PANLONG TOWN,
Nanjing Samwon International Limited
Contact:+86-25-84873444
Address:1108, BLDG B, New Century Plaza, No 1, South Taiping Rd.,
Suzhou HeChuang Chemical Co.,Ltd.
Contact:+86-512-88800520
Address:No.9 Guanchao Rd,Changshu Advanced Materials Industy Park
Rudong Zhenfeng Yiyang Chemical Co., Ltd.
Contact:0513-84573047
Address:South Fengli Town, Rudong County, Jiangsu Province, China
Doi:10.1016/j.bmcl.2010.08.118
(2010)Doi:10.3987/COM-89-5240
(1990)Doi:10.1016/0584-8539(90)80110-K
(1990)Doi:10.1021/ol200567p
(2011)Doi:10.1248/cpb.38.619
(1990)Doi:10.1021/ja00171a040
(1990)
