Journal of Organic Chemistry p. 5894 - 5900 (1990)
Update date:2022-08-03
Topics:
Crimmins, Michael T.
O'Mahony, Rosemary
A general procedure for the synthesis of functionalized spiroketals from lactones is described.Addition of the lithium acetylide of cis-1-methoxy-1-buten-3-yne to lactones followed by a hydration of the acetylene, hydrolysis of the enol ether and cyclizat
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