Journal of Medicinal Chemistry p. 2335 - 2342 (1990)
Update date:2022-09-26
Topics:
Bradbury, Robert H.
Major, John S.
Oldham, Alec A.
Rivett, Janet E.
Roberts, David A.
et al.
A series of inhibitors of human renin have been synthesized, derived from combination of a 2-(8-propyl-6-pyridin-3-yl-1,2,4-triazolo<4,3-a>pyrazin-3-yl)-3-pyridin-3-ylpropionic acid moiety 6c with the hydroxyethylene isostere of the scissile amide bond (2
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(1982)