N-vinyl and N-unsubstituted β-lactams from 1-substituted 2-aza-1,3-butadienes

DOI: 10.1016/0040-4039(90)87005-K

Source and publish data:

Tetrahedron Letters p. 451 - 454 (1990)

Update date:2022-08-02

Topics:

Authors:

Georg Georg

Kant Kant

Mudd Mudd

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Article abstract of DOI:10.1016/0040-4039(90)87005-K

The reaction of acid chlorides and N-vinyl imines results in the stereoselective formation of cis N-vinyl β-lactams. The N-vinyl protecting group can be removed either oxidatively or hydrolytically to yield N-substituted β-lactams.

Full text of DOI:10.1016/0040-4039(90)87005-K

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