73. Metal Complexes of Macrocyclic Ligands. Part XXXIII. Effect of the Side-Chain Length on the On/Off Equilibrium in the Ni2+ and Cu2+ Complexes of 11-(2-Aminoethyl)- and 11-(3-Aminopropyl)-1,4,7,11-tetraazacyclotetradecane

Article abstract of DOI:10.1002/hlca.19900730320

Alkylation of 1,4,7-tritosyl-1,4,7,11-tetraazacyclotetradecane with CH2O/KCN or acrylonitrile gave the corresponding cyanomethyl or 2-cyanoethyl derivatives, which, by treatment with Na in BuOH, were detosylated and reduced to the macrocyclic pentaamines