Tetrahedron Letters p. 911 - 914 (1990)
Update date:2022-08-02
Topics: Chemical Synthesis Dimer ribonucleotides Internucleotidic Phosphorodithioate linkages
Petersen, Kenneth H.
Nielsen, John
Ribonucleosides, chlorobis(amino)phosphines and thiols react via phosphorothioamidites to form phosphorothioites.Oxidation with sulphur gives ribonucleoside phosphorodithioate triesters which after deprotection yields the phosphorodithioate ribonucleoside
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