Synthesis and Anticonvulsant and Sedative-Hypnotic Activity of 4-(Alkylimino)-2,3-dihydro-4H-1-benzopyrans and -benzothiopyrans

DOI: 10.1021/jm00172a030

Source and publish data:

Journal of Medicinal Chemistry p. 2865 - 2869 (1990)

Update date:2022-08-03

Topics:

Authors:

Arnoldi, Anna

Bonsignori, Alberto

Melloni, Piero

Merlini, Lucio

Quadri, Maria Luisa

et al. et al.

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Article abstract of DOI:10.1021/jm00172a030

A series of 4-(alkylimino)-5-hydroxy-7-alkyl-2,3-dihydro-4H-1-benzopyrans and -thiopyrans were synthesized and evaluated for anticonvulsant activity.Preliminary screening of these compounds revealed that 2,2-dimethyl-4-<(2-hydroxyalkyl)imino>-5-hydroxy-7-

Full text of DOI:10.1021/jm00172a030

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