Direct C-Glycosylation of Guanine Analogues: The Synthesis and Antiviral Activity of Certain 7- and 9-Deazaguanine C-Nucleosides

DOI: 10.1021/jm00172a011

Source and publish data:

Journal of Medicinal Chemistry p. 2750 - 2755 (1990)

Update date:2022-09-26

Topics:

Authors:

Girgis, Nabih S.

Michael, Maged A.

Smee, Donald F.

Alaghamandan, Hassan A.

Robins, Roland K.

Cottam, Howard B.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00172a011

C-Glycosylation of two guanine analogues, 9-deaza- and 7-deazaguanine, has been achieved under Friedel-Crafts conditions, providing a direct synthetic route to 9-deazaguanosine (4; 2-amino-7-β-D-ribofuranosyl-5H-pyrrolo<3,2-d>pyrimidin-4(3H)-one) and 8-β-

Full text of DOI:10.1021/jm00172a011

Products guided by the article

Product name:2-chloro-5-Methyl-3H-pyrrolo[3,2-d]pyriMidin-4(5H)-one

Cas No:129872-84-0

R&D Labs maybe for 129872-84-0

QINGDAO NEW FLOURISH INTERNATIOANAL TRADE CO., LTD.

Contact:+86 532 80861829

Address:No. 1, Yinchuan East Road, 266061, Qingdao, China
Zhejiang Newfine Industry Co.,Ltd.

Contact:+86-573-82262042

Address:No.225,Dongqing Road, garoms@163.com
Win-Win chemical Co.Ltd

website:http://www.win-winchemical.com

Contact:0086-577-64498589

Address:6F, No. 396 Xingping Road, Longwan Industrial Zone, Wenzhou City, Zhejiang, 325000 P.R.China
RongCheng K&S Chemical Co.,Ltd

Contact:0631-7336369

Address:rongcheng ,shandong province china
GUANGZHOU MEDCAN PHARMATECH LTD

website:http://www.gzmedcan.com

Contact:+86-20-82519649

Address:Building J,Room 101,1 JiangtashanRd,Guang Zhou Science City,Guang Zhou ,China

Relevant to this article

A microwave-accelerated intramolecular diels-alder reaction approach to compactin

Doi:10.3987/com-95-7257
(1996)
Structure-activity relationship studies of novel 4-[2-[bis(4- fluorophenyl)methoxy]ethyl]-1-(3-phenylpropyl)piperidine analogs: Synthesis and biological evaluation at the dopamine and serotonin transporter sites

Doi:10.1021/jm9506581
(1996)
Reaction of alkylzirconocene cation complexes with (R-C=C-)₂SiR₂ reagents: Preparation of heterodimetallic compounds containing a μ-alkyayl ligand bridge between zirconium and silicon

Doi:10.1002/cber.19961290103
(1996)
Synthesis of D-fructofuranosides using thioglycosides as glycosyl donors

Doi:10.1021/jo951641t
(1996)
Prediction of the solvent dependence of enzymatic prochiral selectivity by means of structure-based thermodynamic calculations

Doi:10.1021/ja952674t
(1996)
Cobalt(II) and copper(II) complexes of 1-nitrobenzyl-2-nitrophenylbenzimidazole: Synthesis, characterization and antibacterial activity studies

Doi:10.1080/00945719608004342
(1996)

Article Doi