Direct C-Glycosylation of Guanine Analogues: The Synthesis and Antiviral Activity of Certain 7- and 9-Deazaguanine C-Nucleosides

DOI: 10.1021/jm00172a011

Source and publish data:

Journal of Medicinal Chemistry p. 2750 - 2755 (1990)

Update date:2022-09-26

Topics:

Authors:

Girgis, Nabih S.

Michael, Maged A.

Smee, Donald F.

Alaghamandan, Hassan A.

Robins, Roland K.

Cottam, Howard B.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00172a011

C-Glycosylation of two guanine analogues, 9-deaza- and 7-deazaguanine, has been achieved under Friedel-Crafts conditions, providing a direct synthetic route to 9-deazaguanosine (4; 2-amino-7-β-D-ribofuranosyl-5H-pyrrolo<3,2-d>pyrimidin-4(3H)-one) and 8-β-

Full text of DOI:10.1021/jm00172a011

Products guided by the article

Product name:2-chloro-5-Methyl-3H-pyrrolo[3,2-d]pyriMidin-4(5H)-one

Cas No:129872-84-0

R&D Labs maybe for 129872-84-0

jintan yufan Medicine Raw materials Co.,Ltd.(expird)

Contact:86-519-82808282

Address:6th,Jincheng Huangzhuang
Reliable Pharma Technology (Shanghai) Co., Ltd.

Contact:0086-21-67676847-8008

Address:Lane 1500, No.68, Xinfei Road, Songjiang District, Shanghai, 201611, P.R.China.
Alway Chem, China

website:http://www.alwaychem.com

Contact:+86-532-8586-4000, 8586-5000

Address:NO.51, TAIPING ROAD, QINGDAO, CHINA. 266001
Changsha Yihai Chemical Technology Co.,ltd

website:http://www.cs-yihai.com/

Contact:0731- 85620465

Address:Room 23005, unit 2, the northern building of Xiangsong international building , NO.259 Shaoshan Road , Changsha , Hunan, China.(mainland)
WUXI KINGHAN BIO-MEDICAL&CHEMICAL INC.

Contact:13861062998

Address:Room 1316,No.1619 Huishan Avenue,Wuxi,China

Relevant to this article

A microwave-accelerated intramolecular diels-alder reaction approach to compactin

Doi:10.3987/com-95-7257
(1996)
Structure-activity relationship studies of novel 4-[2-[bis(4- fluorophenyl)methoxy]ethyl]-1-(3-phenylpropyl)piperidine analogs: Synthesis and biological evaluation at the dopamine and serotonin transporter sites

Doi:10.1021/jm9506581
(1996)
Reaction of alkylzirconocene cation complexes with (R-C=C-)₂SiR₂ reagents: Preparation of heterodimetallic compounds containing a μ-alkyayl ligand bridge between zirconium and silicon

Doi:10.1002/cber.19961290103
(1996)
Synthesis of D-fructofuranosides using thioglycosides as glycosyl donors

Doi:10.1021/jo951641t
(1996)
Prediction of the solvent dependence of enzymatic prochiral selectivity by means of structure-based thermodynamic calculations

Doi:10.1021/ja952674t
(1996)
Cobalt(II) and copper(II) complexes of 1-nitrobenzyl-2-nitrophenylbenzimidazole: Synthesis, characterization and antibacterial activity studies

Doi:10.1080/00945719608004342
(1996)

Article Doi