Journal of the American Chemical Society p. 3366 - 3374 (1996)
Update date:2022-09-26
Topics:
Ke
Wescott
Klibanov
A new, quantitative model is elaborated to rationalize the solvent dependence of enzymatic selectivity solely on the basis of the thermodynamics of substrate solvation. The model predicts that any type of the selectivity (defined as the ratio of k(cat)/K(
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Doi:10.1021/je60035a042
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(1996)Doi:10.1016/0040-4039(96)00430-3
(1996)Doi:10.1055/s-1996-4217
(1996)Doi:10.1016/0040-4039(96)00356-5
(1996)Doi:10.1016/j.molstruc.2011.11.004
(2012)