Journal of Heterocyclic Chemistry p. 1079 - 1083 (1990)
Update date:2022-08-05
Topics:
Quijano
Nogueras
Sanchez
Alvarez de Cienfuegos
Melgarejo
Reactions of 6-amino-3,4-dihydro-2-methoxy-4-oxopyrimidine 1a and its 3-methyl derivative 1b with chloroacetaldehyde and chloroacetyl chloride are discussed in this paper. Amongst others compounds, we have obtained, in low yield, the novel ring system oxazolo[3,2-c]pyrrolo[3,2-e]pyrimidine. The anticancer and anti-microbial activities of some of the obtained products are described.
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Doi:10.1016/S0040-4039(00)89036-X
(1990)Doi:10.1021/jacs.8b05560
(2018)Doi:10.1055/s-0030-1259281
(2011)Doi:10.1016/j.tet.2008.11.062
(2009)Doi:10.1021/jm800937p
(2009)Doi:10.1021/ol801768e
(2008)
