Cyclodehydration of 3-(D-manno-pentitol-1-yl)pyrazoles: synthesis of 3-(D-arabinofuranosyl)pyrazoles

Article abstract of DOI:10.1016/0008-6215(90)84239-Q

Several 3-(D-manno-pentitol-1-yl)pyrazoles were cyclodehydrated by treatment with boiling aqueous 10percent trifluoroacetic acid.The products were α,β-mixtures of 3-(D-arabinofuranosyl)pyrazoles in which the β-anomer was the major component.The structures and configurations of these C-nucleoside analogues were assigned on the basis of their analytical and spectral data, and those of the triacetates.