Stereoselective Free-Radical Cyclization on a Sugar Template The Suphonyl Radical as a Synthetic Tool for Functionalized Glycosides

Article abstract of DOI:10.1016/S0040-4039(00)94437-X

The addition of a sulphonyl radical to the external double bond of an allyl glycal generates a pro-chiral carbon radical which adds to the glycal double bond with a high diastereoselectivity.Through three consecutive radical steps, the configurations of three new asymmetric centers are controlled.