Analogues of sialic acids as potential sialidase inhibitors synthesis of 2-C-hydroxymethyl derivatives of N-acetyl-6-amino-2,6-dideoxy-neuraminic acid

Article abstract of DOI:10.1002/hlca.19900730422

The intramolecular cycloaddition of the previously described azidoalkene 16, the related diacetates 7 and 13, and the monoacetate 8 led diastereoselectively to the (2R-) and (2S)-configurated hydropyridotriazoles 17, 9 and 11, 14 and 15, and 10 and 12, re