Solvent, not palladium oxidation state, is the primary determinant for successful coupling of terminal alkynes with iodo-nucleosides

DOI: 10.1016/S0040-4039(00)97456-2

Source and publish data:

Tetrahedron Letters p. 3731 - 3734 (1990)

Update date:2022-07-29

Topics:

Authors:

Robins, Morris J.

Vinayak, Ravi S.

Wood, Steven G.

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Article abstract of DOI:10.1016/S0040-4039(00)97456-2

Coupling of iodo-nucleosides with terminal alkynes such as 3-(acylamino)propynes, whose initial products readily undergo secondary cyclization reactions, can be effected smoothly by the standard catalysis with (Ph₃P)₂PdCl₂

Full text of DOI:10.1016/S0040-4039(00)97456-2

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