Journal of Organic Chemistry p. 5603 - 5613 (2019)
Update date:2022-08-02
Topics:
Nimnual, Phongprapan
Tummatorn, Jumreang
Boekfa, Bundet
Thongsornkleeb, Charnsak
Ruchirawat, Somsak
Piyachat, Pawida
Punjajom, Kunlayanee
A novel synthetic approach for the synthesis of 5-aminotetrazoles has been developed by employing simple ketones as substrates. This methodology involved the N2-extrusion/aryl migration of azido complexes as the key step for the in situ generation of carbodiimidium ion, which could further react with hydrazoic acid and cyclize intramolecularly to provide 5-aminotetrazoles in good to excellent yields. In addition, the regioselectivity of the reaction was studied and rationalized by density functional theory calculations.
View MoreHangzhou Think Chemical Co. Ltd
website:http://www.thinkchem.com/
Contact:86-571-89986307/81956191/81956084/81956192
Address:Room 501-502, Tower E, Yuanjian Building, Yuanyang International Center, Hangzhou-310011, China
Contact:+49-9398-993127
Address:Untertorstr. 27
Shanghai Mio Chemical Co., Ltd
Contact:0086 21- 64401188-622
Address:16 Floor NO.2 Jiefang Building, No. 4855 Dushi Road, 201100 Shanghai, P.R.China
JiYi Chemical (Beijing) Co., Ltd.
Contact:+86-10-89385733
Address:Shilou Town of Fangshan District, Beijing
Nanjing lanbai chemical Co.,Ltd.
Contact:+86-25-85499326
Address:Room 908, 9F Taiyue Building,No.285 Heyan Road
Doi:10.1134/S107036321103025X
(2011)Doi:10.1080/14756366.2019.1681988
(2020)Doi:10.24820/ark.5550190.p010.618
(2018)Doi:10.1021/acs.orglett.5b03685
(2016)Doi:10.3987/COM-16-13515
(2016)Doi:10.1021/jo00081a007
(1994)