Tetrahedron p. 1361 - 1370 (1984)
Update date:2022-07-29
Topics: Synthesis Alkylation Catalyst Enantioselective Nucleophile Reaction Conditions Chiral Ligand Spectroscopic Analysis
Meyers, A. I.
Fuentes, Lelia M.
Kubota, Yoshikazu
A series of chiral amino alcohols transformed into the formamidine derivative of 1,2,3,4-tetrahydroisoquinolines were evaluated as chiral dipole-stabilized anions.Alkylation with alkyl halides provided the 1-alkyl-1,2,3,4-tetrahydroisoquinolines in both e
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