
Chemical and Pharmaceutical Bulletin p. 2550 - 2555 (1991)
Update date:2022-07-29
Topics: Synthesis Chiral Experimental Renin inhibitors C-Terminal Component
Kobayashi
Matsumoto
Takemoto
Nakatani
Ito
Kamijo
Harada
Terashima
The addition reaction of cyclohexylmethylmagnesium bromide with the imine prepared from unnatural (2S,3S)-tartaric acid was found to proceed in a highly stereoselective manner in the presence of cerium(III) chloride. A chelation-controlled mechanism could
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