Cyclometallated compounds VI. Cyclopalladation of 2-phenylpyrimidines with pendant pyrazole donors

Article abstract of DOI:10.1016/0022-328X(90)85300-N

The use of pendant pyrazole groups to induce double cyclopalladation of 2-phenylpyrimidines has been investigated. 4,6-Bis(pyrazol-1-yl)-2-phenylpyrimidine undergoes monocyclopalladation only, whilst 4-methyl-2-phenyl-6(pyrazol-1-ylmethyl)pyrimidine react