Minor structural differences in Boc-CCK-4 derivatives dictate affinity and selectivity for CCK-A and CCK-B reeeptors

DOI: 10.1021/jm960509y

Source and publish data:

Journal of Medicinal Chemistry p. 1169 - 1172 (1997)

Update date:2022-08-04

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Authors:

Shiosaki

Chun Wel Lin

Kopecka Kopecka

Bianchi Bianchi

Miller Miller

Stashko Stashko

Witte Witte

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Article abstract of DOI:10.1021/jm960509y

We previously reported novel Boc-CCK-4 (Boc-Trp-Met-Asp-Phe-NH₂) derivatives possessing the general structure Boc-Trp-Lys[Nε-CO-NH-(R-Ph)]- Asp-Phe-NH₂ (Shiosaki et al. J. Med. Chem. 1991, 34, 2837-2842). In contrast to Boc-CCK-4, wh

Full text of DOI:10.1021/jm960509y

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