Fedrazole Hydrochloride: A Potent, Selective, Nonsteroidal Inhibitor ofAromatase for the Treatment of Estrogen-Dependent Disease

DOI: 10.1021/jm00106a038

Source and publish data:

Journal of Medicinal Chemistry p. 725 - 736 (1991)

Update date:2022-07-29

Topics:

Authors:

Browne, L. J.

Gude, C.

Rodriguez, H.

Steele, R. E.

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Article abstract of DOI:10.1021/jm00106a038

A new class of potent, selective, nonsteroidal inhibitors of aromatase have been discovered.The most potent member of this series is fadrozole hydrochloride, CGS 16949 A, 4-(5,6,7,8-tetrahydroimidazo<1,5-a>pyridin-5-yl)benzonitrile monohydrochloride, 26a.

Full text of DOI:10.1021/jm00106a038

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