Yb(CN)3-catalyzed reaction of aziridines with cyanotrimethylsilane. A facile synthesis of optically pure β-amino nitriles

Article abstract of DOI:10.1016/S0040-4039(00)97069-2

Reaction of a N-tosylaziridine with cyanotrimethylsilane under lanthanoid tricyanide catalysis gives a N-tosyl β-amino nitrile by selective attack of cyanide at less substituted carbon of the ring; optically pure 2-substituted aziridine affords the corres