Tetrahedron Letters p. 6931 - 6934 (1990)
Update date:2022-08-04
Topics:
Wilson, F. X.
Fleet, G. W. J.
Vogt, K.
Wang, Y.
Witty, D. R.
et al.
A low yield synthesis of oxetanocin and its α-epimer by reaction of adenine with a protected 3-hydroxymethyl-2-chlorooxetane is described; attempts to synthesise other C-2'alkyl analogues of oxetanocin by analogous reactions indicate a limitation of this strategy for the synthesis of oxetane nucleosides.An intermediate for the synthesis of C-nucleoside analogues of oxetanocin is reported.
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