Tetrahedron p. 9753 - 9766 (1992)
Update date:2022-08-05
Topics:
Branden, Stefan Van den
Compernolle, Frans
Hoornaert, Georges J.
This report describes the synthesis of pharmacologically interesting 2,5-substituted piperidines from cis and trans ethyl 1-benzyl-6-cyano-3-piperidinecarboxylate 4.Reduction and p-fluorobenzoylation of 4 led to the primary alcohols 7.The alcohols were tr
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