
Heterocycles p. 1565 - 1569 (1990)
Update date:2022-08-02
Topics:
Strekowski, Lucjan
Wydra, Roman L.
Harden, Donald B.
Honkan, Vidya A.
The title compounds (3) are produced in a novel, lithium alkylamide- and dialkylamide-mediated cyclization of N-(1,2,3,4-tetrahydro-1-naphthylidene)-2-trifluoromethylaniline (2).The mechanism of this unusual transformation that involves the trifluoromethyl group is discussed.
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Doi:10.1016/j.tet.2011.06.017
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(2011)