2-Acetylpyridine thiosemicarbazones. 13. Derivatives with antifilarial activity

DOI: 10.1021/jm00108a027

Source and publish data:

Journal of Medicinal Chemistry p. 1422 - 1425 (1991)

Update date:2022-09-26

Topics:

Authors:

Klayman, Daniel L.

Ai, J. Lin

McCall, John W.

Wang, Shao-Yin

Townson, Simon

et al. et al.

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Article abstract of DOI:10.1021/jm00108a027

Several members of a series of 2-acetylpyridine thiosemicarbazones possess in vivo and in vitro macrofilaricidal properties.The most promising of the group tested is N⁴-(2-aminophenyl)-2-<1-(pyridinyl)ethylidene>-hydrazinecarbothioamide (4), wh

Full text of DOI:10.1021/jm00108a027

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