Asymmetric Tandem Additions to Chiral Naphthyloxazolines. A New and Potent Chiral Auxiliary Resulting in a Major Improvement in Convenience and Efficiency

Article abstract of DOI:10.1021/jo00007a010

Excellent diastereofacial selectivities over a wide range of temperatures (-78 to 25 deg C) were obtained with the title compounds with use of chiral oxazolines derived from (S)-valinol or (S)-tert-leucinol.These are the first useful levels of asymmetric