Synthesis and pharmacological evaluation of 4,4a-dihydro-5H-benzopyranopyridazin-3-(2H)-ones bioisosters of antihypertensive and antithrombotic benzocinnolinones

DOI: 10.1016/0223-5234(90)90194-8

Source and publish data:

European Journal of Medicinal Chemistry p. 749 - 756 (1990)

Update date:2022-08-03

Topics:

Authors:

Cignarella, G

Barlocco, D

Curzu, M M

Pinna, G A

Cazzulani, P

et al. et al.

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Article abstract of DOI:10.1016/0223-5234(90)90194-8

A series of 4,4a-dihydro-5H-<1>benzopyrano<4,3-c>pyridazin-3-(2H)-ones (2a-h), have been prepared and evaluated for their pharmacological profile as antihypertensive and antithrombotic agents.Compounds 2 were ineffective in lowering the blood pressure of

Full text of DOI:10.1016/0223-5234(90)90194-8

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