European Journal of Medicinal Chemistry p. 261 - 271 (1991)
Update date:2022-07-29
Topics: Synthesis NMR spectroscopy X-ray crystallography Biological Evaluation Animal Models Cell culture assays Netropsin
Debart
Gosselin
Rayner
Le Ber
Auclair
Balzarini
De Clercq
Paoletti
Imbach
A series of oligo-meta-benzamides structurally related to the natural agent netropsin have been synthesized. Their binding constants to double-stranded polynucleotides as well as their cytostatic activity against tumor cell lines and their in vitro activi
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