Animal Models

Synthesis Lipase Medicinal chemistry Amino acids Inhibitors NMR spectroscopy Mass spectrometry Selectivity Optimization Potency Organic synthesis HPLC (high-performance liquid chromatography) X-ray crystallography Peptides Cell Culture Structure-Activity Relationship (SAR) Analysis Mechanistic Studies Chemical Synthesis Biological Assays Structure-Activity Relationship (SAR) Studies Clinical Trials High-Throughput Screening Clinical Development Literature Review Biological Evaluation In Vivo Studies Lead Optimization Lead Compound Selection Regulatory Approval In Vitro Assays Pharmacokinetics and Toxicology Pharmacokinetics Pharmacological Properties Design and Synthesis Background Pyrrolidine-Based Compounds T-type calcium channels are low-voltage activated calcium channels, and they are divided into three subtypes Safety and Toxicology Publication and Clinical Development Future Potential Biochemical Assays Preclinical Testing Pharmacokinetic and Toxicity Studies Cell-Based Assays Toxicity and Selectivity In Vivo Assays Compound Screening Cell Lines Potent Publication and Collaboration